The Lancet Rheumatology. Stevenson M, Archer R, Tosh J, Simpson E, Everson-Hock E, Stevens J, et al. You can email the site owner to let them know you were blocked. Scand J Rheumatol. Anti-survival motor neuron complex antibodies as a novel biomarker for pulmonary arterial hypertension and interstitial lung disease in Mixed connective tissue disease, Assessment of digital perfusion as a surrogate outcome in Raynauds phenomenon clinical trials, New-onset atrial fibrillation in seropositive rheumatoid arthritis: association with disease-modifying anti-rheumatic drugs treatment, When spondyloarthritis presents as a complex and multi-system disease, About the British Society for Rheumatology, British Society for Rheumatology Journals, https://doi.org/10.1093/rheumatology/kead011, https://www.gov.uk/government/publications/english-indices-of-deprivation-2019-technical-report, https://academic.oup.com/pages/standard-publication-reuse-rights, Receive exclusive offers and updates from Oxford Academic, Copyright 2023 British Society for Rheumatology. PubMed Article Meta-regressions were conducted to assess the impact of treatments on the ACR70 response in a manner adjusted to the baseline HAQ score, study follow-up time (total study duration), and frequency of TNFi treatment in the control arm (Additional file 1: Fig. Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. 2010;37:91727. Health & Parenting Guide - Your Guide to Raising a Happy - WebMD 2023;62:2394-2401. However, when therapies have a similar efficacy, it is worth minimizing the risk of false negative results [41]. The Brooks-Gelman-Rubin method [17] was used for the convergence diagnostics. However, the relationship between anti-CarPA and other rheumatic diseases (RDs . Jakobsen JC, Gluud C, Wetterslev J, Winkel P. When and how should multiple imputation be used for handling missing data in randomised clinical trials - a practical guide with flowcharts. Your IP: Ethical Approval and consent to participate were not included in the protocol since all data. In the case of TNFi users, it is more obvious to think that marginal gain with a second bDMARDs will be smaller than individuals not taking TNFi. Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximabs Efficacy in MTX iNadequate rEsponders (SERENE)). Click to reveal Social factors play a crucial role as shown increasingly by a large body of evidence [1]. These 3 explanatory variables were found after exploring all potential predictors of ACR70 response such as percentage of women, glucocorticoid use, patients' age, MTX dose, duration of RA, baseline HAQ, baseline DAS28, study follow-up time and frequency of TNFi treatment in the control arm. Journal ISSN: 1462-0324 About Rheumatology Rheumatology is an international peer review journal publishing the highest quality scientific and clinical papers. 2. . The realities of risk-cost-benefit analysis. 2014;41:21626. Recent Articles - The Lancet Rheumatology - Journal - Elsevier Cloudflare Ray ID: 7e3f69f93b2f02d7 All rights reserved. Med Decis Making. statement and to be driven by the subjective components of this composite index, namely the tender joint count and visual analogue scale general wellbeing, rather than swollen joint counts or CRP levels. Discover the latest rheumatoid arthritis research from Rheumatology and Rheumatology Advances in Practice. PubMed However, adiposity (fatness) is not necessarily truly reflected in level of BMI. 2023 BioMed Central Ltd unless otherwise stated. 2.9- 5-year Impact Factor . S1. Click to reveal Part of Visit the ACR Abstracts website. The ACR score measures the rheumatic disease activity and is used to measure differences in relation to the baseline, showing a good relationship with the quality of life and functionality [12]. Given the association between obesity and other comorbidities such as cardiovascular disease also increased in patients with RA [11], and the potential impact on treatment choice, it is necessary that obesity is adequately addressed in routine clinical care. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. S4A) and each additional month of follow-up was associated with a RR of 0.980 (95% CI 0.9610.996, p for difference=0.048, R2=9%, I2=71%, p for heterogeneity0.001) for achieving an ACR70 response. Latest tweets Tweets by RheumJnl . Pages: 207-447 February 2023 Issue Volume 5, Issue 2 Pages: 59-102 February 2023 volume63, Articlenumber:30 (2023) A journal impact factor is frequently used as a proxy for the relative importance of a journal within its field. [38], where authors compared the effectiveness and safety of RTX, ABA, and TCZ in a population of patients with RA refractory to treatment with TNFi agents. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. Find out more: What is a good impact factor? Impact-Faktor IF Analyse, Trend, Ranking & Vorhersage. A narrative review, Association of high body mass index with decreased treatment response to combination therapy in recent-onset rheumatoid arthritis patients, 2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis, 2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases, Social deprivation, gender and obesity: multiple stigma? Schiff M, Keiserman M, Codding C, Songcharoen S, Berman A, Nayiager S, et al. The scope of Rheumatology includes a range of rheumatological conditions, musculoskeletal medicine, surgery and translational research. EMEUNET | Top Journals in Rheumatology - EULAR This website is using a security service to protect itself from online attacks. Arthritis Care and Research - Impact Factor, Overall - Resurchify 12. In this sense, the aim of this study is to perform a systematic review seeking to evaluate randomized clinical trials (RCTs) on the efficacy of RTX, TCZ, and ABA in individuals with RA refractory to MTX or TNFi therapies. S4C). 2008;371:98797. Frontiers | Distribution and clinical significance of anti N Engl J Med. 2010;39:42541. suggests that in people living in more deprived areas, obesity further associates with worse disease outcomes. Finally, the longer the exposure time to bDMARDs after 6months may increase the chance to identify new individuals with disease flares or therapy failures. Pugliesi, A., de Oliveira, A.B., Oliveira, A.B. Version 5.1.0 (updated March 2011), The Cochrane Collaboration, Chichester (UK); 2011. Dias S, Sutton AJ, Welton NJ, Ades AE. Semin Arthritis Rheum. Among the 19 selected trials, 31.5% (six) included TCZ as intervention arm, 31.5% (six) included RTX as active arm, and 31.5% (six) included ABA as intervention arm. Lancet. Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: results from the SUNRISE trial. Arthritis & Rheumatology - Wikipedia Methods. The secondary outcomes were the ACR50 and ACR20 response criteria compared among treatments to identify differences in the ACR response pattern. Research Impact Score*: 6.2. BMC Rheumatology is an open access, peer-reviewed journal that considers pre-clinical, translational and clinical articles on all aspects of the prevention, treatment and management of rheumatological diseases, related systemic and inflammatory conditions and associated comorbidities, as well as epidemiology, education, pathophysiology, genetics. GC: received speaker fees from AbbVie, Pfizer, BMS, Roche, Lilly, and Novartis; LSFC: Speaker/Consultant fees from Abbott, American Heart Association, Roche, Amgen, NovoNordisk, Libbs. 2013;33:61840. PubMed In other words, it is not solely the biological and genetic make-up that define health status. Multiple components of deprivation (e.g. the productivity and citation impact of the publications of a Preventing rheumatoid arthritis: Lessons from that of type 1 diabetes Article 2010;376:1094108. We acknowledge all support received by Brazilian Society of Rheumatology. The latest impact factor of Arthritis and all the other SCI journals was released on 30th June 2022 by Clarivate. 2016;45:2626. Research Grants from BMS. Ann Rheum Dis. Stat Med. Research Ranking (Immunology) 40. Brief report: rheumatoid arthritis response criteria and patient-reported improvement in arthritis activity: is an American College of Rheumatology twenty percent response meaningful to patients? As a final reflection, it is important to keep in mind that causality cannot be proven based on these observations, and this is in fact a common problem with observational data, especially with much residual confounding and other biases such as confounding by indication. Notes from the Field. This collection brings together cutting-edge articles from the BSR journals, with a focus on difficult-to-treat RA, real world data, the role of imaging . MAGG: has received research support from AbbVie, MSD, Jansen and Roche, and has received consultation fees or has participated in a company-sponsored speakers bureau from AbbVie, Pfizer, Roche, Sanofi, Celgene, Sobi and MSD. Actigraphy-derived physical activity levels and circadian rhythm Despite pointing to a similar effectiveness among drugs, it is important to highlight that few data were available at the time of publication of these studies, with their low statistical power suggesting a risk of type II error greater than 30%. Performance & security by Cloudflare. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging.. 74. As shown in Additional file 1: Figure S3A-S3C, there was no significant publication bias in funnel charts and no significant small-study bias according to the Egger tests. It is an official journal of the American College of Rheumatology . Science. Through this web page, researchers can check the impact factor, total citation, journal quartile, and journal aim & scope. Arthritis & Rheumatology is a monthly peer-reviewed medical journal covering the natural history, pathophysiology, treatment, and outcome of the rheumatic diseases. scijournal.org is a platform dedicated to making the search and SCIMAGO H-index: 158. Munich, Bavaria, Germany Monthly Weather | AccuWeather Arthritis Rheum. The journal publishes high-quality articles reporting on original investigations in all aspects of rheumatology-related research (basic science, clinical science, epidemiology, health outcomes, health policy, and education) as well as reviews and commentaries. https://doi.org/10.1136/bmj.n71. Article Social factors play a crucial role as shown increasingly by a large body of evidence . 69.163.163.2 Hospital de Clnicas, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil, Neurosurgery Unit of the Hospital de Base Do Distrito Federal Base, Braslia, DF, Brazil, Health Sciences Research and Teaching Foundation of Braslia (ESCS/FEPECS), Braslia, DF, Brazil, Ana Beatrice Oliveira&Luiz Sergio Fernandes de Carvalho, Rheumatology Service, Federal University of Rio Grande Do Sul, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, Hospital Universitrio de Braslia, University of Braslia (HUB-UnB-EBSERH), Braslia, DF, Brazil, Medical Sciences at Faculty of Medicine, University of Braslia (UnB), Braslia, DF, Brazil, Division of Rheumatology, Hospital Universitrio Marqus de Valdecilla, IDIVAL, Universidad de Cantabria, Santander, Spain, Section of Rheumatology, Instituto de Rheabilitacion Psicofisica, Buenos Aires, Argentina, Laboratory of Data for Quality of Care and Outcomes Research (LaDaQCOR), Catholic University of Braslia (UCB), QS 07, Lote 01, Taguatinga Sul-Taguatinga, Braslia, DF, 71966-700, Brazil, Medical Data Analyst, Data Lab, Clarity Healthcare Intelligence, Jundiai, SP, Brazil, You can also search for this author in Explore the latest in rheumatology, including advances in therapy for rheumatoid and psoriatic arthritis and other connective tissue diseases. Arthritis and Rheumatology Impact Factor: scientometric | Exaly It is also important to understand the existing heterogeneity among trials, finding ways to mitigate it to allow an adequate comparison among treatments. Terms and Conditions, A suggested explanation centres on links between adiposity and inflammation and immunological changes that may drive active disease [6]. Porter D, van Melckebeke J, Dale J, Messow CM, McConnachie A, Walker A, et al. We have seen a revolution in drug therapies and treatment strategies over the years, as part of attempts to improve patient care and treatment outcomes. From choosing baby's name to helping a teenager choose a college, you'll make . Assessment of rituximabs immunomodulatory synovial effects (ARISE trial). can be difficult to interpret, especially with other parameters such as waist circumference (which has been shown to more strongly associate with inflammation) missing. PubMed Central In: Higgins JPT, Green S, editors. Rheumatology & Autoimmunity, hosted by Chinese Medical Association, is a peer-reviewed, open access journal focusing on cutting-edge research in rheumatology and autoimmune diseases. 2016;388:34355. Performance & security by Cloudflare. We searched 6 databases until January 2023 for phase 24 RCTs evaluating patients with RA refractory to MTX or TNFi therapy treated with rituximab, abatacept, and tocilizumab (intervention arm) compared to controls. Results of a population survey from Germany, Early Rheumatoid Arthritis Study and the Early Rheumatoid Arthritis Network Cohorts, Secular changes in clinical features at presentation of rheumatoid arthritis: increase in comorbidity but improved inflammatory states, The outcomes of bariatric surgery on rheumatoid arthritis disease activity: a prospective cohort study, The Author(s) 2023. Arthritis and Rheumatology 2022-2023 | | | Traditionally used as a first-line treatment after methotrexate (MTX) failure, therapy with tumor necrosis factor inhibitors (TNFi) improves the quality of life of most individuals with RA. Secretaria de Cincia, Tecnologia e Insumos Estratgicos. Cloudflare Ray ID: 7e3f6a00d90c3c45 There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. Such comparisons, unfortunately, will probably never be carried out. A potential explanation, as the authors discuss, is that RA patients who are obese may be less responsive to anti-rheumatic treatment, as supported by existing evidence [7]. Thus, heterogeneity was attenuated (I2=24%) and the explanatory power of the model increased (R2=85%). 2010;69:15808. Arthritis Care & Research - Wiley Online Library The term search was focused on titles, keywords, and abstracts. Therefore, the association between obesity and CRP levels observed by Witkam et al. 2015;350:aaa6516. When indirectly compared to each other, ABA vs. RTX show a HR of 1.013 (95% CI 0.6691.535 p=0.890) and TCZ vs. ABA show a HR of 1.014 (95% CI 0.6261.618 p=0.92). Data extracted from studies were inserted, organized, and standardized in a Microsoft Excel (Microsoft Corporation, OneMicrosoftWay Redmond, Washington, EUA) spreadsheet. The high variability in the relative treatment effects threatens the external validity of the study evidence and limits its generalization [42]. Advertisement intended for healthcare professionals, Centre for Rheumatic Diseases, Kings College London, Rheumatology Department, Kings College Hospital. Rheumatoid arthritis. BMI mediated 1417% of the associations of deprivation with disability and disease activity, suggesting that obesity explains at least part of the association between deprivation, disability and disease activity. Published by Oxford University Press on behalf of the British Society for Rheumatology. This website is using a security service to protect itself from online attacks. In health and disease, both biological and non-biological factors play an important role. BMC Med Res Methodol. 2010;29:93244. Emery P, Fleischmann R, Filipowicz-Sosnowska A, Schechtman J, Szczepanski L, Kavanaugh A, et al. Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: two-year efficacy and safety findings from AMPLE trial. Arthritis & Rheumatology: Vol 75, No 6 - Wiley Online Library Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Some important limitations must be emphasized. Impact Factor (IF) Total Articles: Total Cites: 2022 (2023 update)--2021--2020--2019--2018--2017--2016--2015: 8.955: 0: 45624: 2014: 7.764: 0: 46886: 2013: 7.871: 331: 46884: 2012: 7.477: 411: 45200: 2011: 7.866: 406: 43887: 2010: 8.435: 382: 44602 In the second stage, the investigators independently evaluated the full text of the articles and made their selections according to the pre-specified eligibility criteria. Disclosure statement: The authors have declared no conflicts of interest. Arthritis and Rheumatology Impactfactor 2022-2023 | Analyse, Trend The NMA showed no significant difference among the studied drugs in achieving an ACR70 response, therefore, they have a similar effectiveness, with low inconsistency, but high heterogeneity among studies. received by a journal and the importance or prestige of the journals where Research Highlight 22 May 2023 Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies Sathish Muthu Jasmijn V. Korpershoek Ivan Martin Review Article 09 Jun. Thus, the absence of head-to-head trials between RTX, ABA and TCZ and the low statistical power of previous NMA make a new assessment of published studies and a new study analyzing the combination of the efficacy of such drugs essential. Drafting of the manuscript: LSFC, ABO, AP. Arthritis & Rheumatology - Wiley Online Library With the present results, it is advisable to evaluate the introduction ABA or RTX before TCZ in refractory RA. 2-5 In these studies, individuals at risk for RA were identified mainly by the detection . You can email the site owner to let them know you were blocked. Brasil. Number of Best scientists*: 119. Google Scholar. Full systematic review data and codes in R for data processing and meta-analysis are available under request. In this study, a systematic review was carried out using a NMA to compare the efficacy of RTX, TCZ, and ABA in individuals with RA refractory to treatment with TNFi agents or MTX. Arthritis and Rheumatology - Impact Factor, Overall Ranking, Rating, h The first study selection stage consisted of reading the titles, further encompassing abstracts and keywords. In contrast, abatacept was associated with RR=2.217 (95%CI 1.5543.161, p<0.001) for ACR70 compared to tocilizumab. MBB: Has participated in clinical and/or experimental studies related this work and sponsored by Roche; has delivered speeches at events related to this work and sponsored by AbbVie and Pfizer. Best Practice & Research Clinical Rheumatology | Journal Diretrizes Metodolgicas. Performance & security by Cloudflare. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. During the extraction of information from the studies, some data were not available for all trials, and the analysis of only English published trials can generate a systematic data collection bias. Ann Rheum Dis. This study followed PRISMA statement [11]. Luiz Sergio Fernandes de Carvalho. A longitudinal cohort study, by Witkam et al. Non-inflammatory pain in inflammatory arthritis | Rheumatology | Oxford Google Scholar. Yet, considering the broad inclusion criteria, which resulted in a study population that best resembles real patients, and the choice of viable interventions, in the case of clinical trials, the results of this study have external validity with applicability in daily practice. 2006;54:1390400. Rheumatology Impact Factor IF 2023|2022|2021 - BioxBio 1: clinical and synovial biomarker results. However, it is also known that obesity is socially patterned, so targeting those most at risk, including those of lower socioeconomic status through public health campaigns, self-management interventions [8] and other lifestyle changes [9] will likely be of benefit. 2002;46:14709. Trial-based cost-effectiveness of abatacept for rheumatoid arthritis patients in Italy. Bijlsma JWJ, Welsing PMJ, Woodworth TG, Middelink LM, Peth-Schramm A, Bernasconi C, et al. Other meta-analyses of randomized or observational studies [9, 10] presented a low quality and/or highly heterogeneous data. Largely, comparisons among treatments were focused on the effectiveness of TNFi vs. non-TNFi agents. Indirect comparisons of the efficacy of biological antirheumatic agents in rheumatoid arthritis in patients with an inadequate response to conventional disease-modifying antirheumatic drugs or to an anti-tumour necrosis factor agent: a meta-analysis. Lancet. The Journal of Rheumatology is owned by the Canadian Rheumatology Association Foundation, a charity dedicated to supporting research, education, and care delivery by rheumatology professionals for people with rheumatic diseases. Psoriatic Arthritis Quality of Life questionnaire: Translation - PubMed The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Ministrio da Sade. Rheumatology maintains a focus on high societal impact in the form of contextual podcasts, videos and extended social media presence, and utilizing alternative metrics to support dissemination from Day 1 of publication. This is irrespective of the socioeconomic background of people living with the disease, albeit potentially with a sense of priority in those of lower socioeconomic status. To identify all RCTs that assess the relationship between the efficacy of RTX, TCZ, and ABA in individuals with RA refractory to treatment with TNFi agents or MTX, searches for original articles were conducted in the MedLine (PubMed), Cochrane Library, Embase, Web of Science, Scopus, and Latin American and Caribbean Literature in Health Sciences (LILACS) databases until January 12, 2023. Besides, the baseline HAQ score was significantly lower (ABA 1.680.15, RTX 1.680.23, and TCZ 1.500.17; p=0.049). We excluded literature reviews, editorials, conference records, congress annals or abstracts, in vitro and animal model studies, qualitative studies, cross-sectional studies, casecontrol studies, systematic reviews, studies that evidenced alternative treatments using antibiotics, studies with an exposure time of less than 24weeks, researches that considered patients with other types of autoimmune diseases, investigations of the use of TCZ, RTX, or ABA to treat other diseases, studies that included patients with comorbidities (pregnancy, breastfeeding, histoplasmosis, coccidioidomycosis, HIV, tuberculosis etc. Statistical analyses were performed using the R Studio software, version 1.1.4 (R v.4.0.1 and R_Studio v.1.1.463, Auckland, NZ) [19]. Grading of recommendations assessment: development and evaluation, Latin American and Caribbean literature in health sciences, Preferred reporting items for systematic reviews and meta-analyses, Prospective register of systematic reviews. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. Though meta-regression results should be understood as an hypothesis-generating evidence, they enable testing a scenario where components of heterogeneity among RCTs become more balanced. Performance & security by Cloudflare. Sistema GRADE manual de graduao da qualidade da evidncia e fora de recomendao para tomada de deciso em sade. On the other hand, comparisons among the three non-TNFi agents showed a statistical power<65%. Our Immediacy Index (average number of times an article is cited in the year it is published) has also increased from 0.568 to 1.236. For all analyses, there was a slight inconsistency between direct and indirect measures (Table 1, Indirect comparisons among bDMARDs), but they showed a substantial heterogeneity among RCTs (>40%) (Additional file 1: Fig. J Rheumatol. You can email the site owner to let them know you were blocked. Lindegaard HM, Johansen P, Grndal G, Jensen EC, Juul L, Schlemmer AM, Agular B, Hansen I. Your privacy choices/Manage cookies we use in the preference centre. De Impactfactor voor 2022-2023 van Arthritis and Rheumatology is 15.483 More Impactfactor Analyse, Trend, Ranglijst & Voorspelling. 1 Hence, research efforts have been devoted to investigation of whether intervention starting at the preclinical stage will prevent the clinical onset of RA. Arthritis Care Res. In this model, ABA did not modify the chance of achieving an ACR70 response when compared to RTX (1.773, 95% CI 0.11310.21, p=0.765). most cited papers and the number of citations that they have received Checking consistency in mixed treatment comparison meta-analysis. Thank you to all our authors, reviewers and Editors who have made such valuable contributions to the journal! To control these unbalanced characteristics, multivariate meta-regression adjusted to these 3 factors were performed and showed that ABA was associated with RR of 2.22 (95% CI 1.553.16, p<0.001) for ACR70 compared to TCZ, with attenuated heterogeneity and high explanatory power. [1] Arthritis and Rheumatology - SciRev Braslia: Ministrio da Sade; 2014. http://bvsms.saude.gov.br/bvs/publicacoes/diretrizes_metodologicas_sistema_grade.pdf. The impact score (IS) 2022 of Arthritis Care and Research is 3.78, which is computed in 2023 as per its definition. However, the statistical power achieved in this study suggests that chances of false negative results are extremely low. 2016;16:40917. Kavanaugh A, Rosengren S, Lee SJ, Hammaker D, Firestein GS, Kalunian K, et al. 1 It is understood that underlying endothelial dysfunction secondary to chronic . Thank you for submitting a comment on this article. Means and standard deviations were used to represent variables within the RCTs. Health Econ. Comparative effectiveness of rituximab, abatacept, and tocilizumab in adults with rheumatoid arthritis and inadequate response to TNF inhibitors: prospective cohort study. About. A longitudinal cohort study, Do associations between education and obesity vary depending on the measure of obesity used? Using data from the multicentre, prospective observational cohort Rheumatoid Arthritis Medication Study (RAMS) over 12months, Witkam et al. The Journal of Rheumatology Firstly, there is a high degree of heterogeneity among studies for all drugs. However, we reiterate the important message here, in that obesity seems to be an important factor in the association between social disparities and adverse disease outcomes in RA. R Core Team (2022). Arthritis Rheumatol. These are limitations and prevent a more comprehensive understanding of the role of individual socioeconomic factors. ; Oxford University Press is a department of the University of Oxford. Compared efficacy of rituximab, abatacept, and tocilizumab in patients with rheumatoid arthritis refractory to methotrexate or TNF inhibitors agents: a systematic review and network meta-analysis.
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